Automated hexahedral meshing of anatomic structures using deformable registration

Abstract

This work introduces a novel method of automating the process of patient-specific finite element (FE) model development using a mapped mesh technique. The objective is to map a predefined mesh (template) of high quality directly onto a new bony surface (target) definition, thereby yielding a similar mesh with minimal user interaction. To bring the template mesh into correspondence with the target surface, a deformable registration technique based on the FE method has been adopted. The procedure has been made hierarchical allowing several levels of mesh refinement to be used, thus reducing the time required to achieve a solution. Our initial efforts have focused on the phalanx bones of the human hand. Mesh quality metrics, such as element volume and distortion were evaluated. Furthermore, the distance between the target surface and the final mapped mesh were measured. The results have satisfactorily proven the applicability of the proposed method.

Keywords:

• finite element
• mapped mesh
• biomechanics
• bone

Acknowledgements

The authors gratefully acknowledge financial support provided by Award R01EB005973 from the National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health. The authors would like to acknowledge the contributions of Nicole DeVries.