Implementation of asymmetric yielding in case-specific finite element models improves the prediction of femoral fractures

Abstract

Although asymmetric yielding in bone is widely shown in experimental studies, previous case-specific non-linear finite element (FE) studies have mainly adopted material behaviour using the Von Mises yield criterion (VMYC), assuming equal bone strength in tension and compression. In this study, it was verified that asymmetric yielding in FE models can be captured using the Drucker–Prager yield criterion (DPYC), and can provide better results than simulations using the VMYC. A sensitivity analysis on parameters defining the DPYC (i.e. the degree of yield asymmetry and the yield stress settings) was performed, focusing on the effect on bone failure. In this study, the implementation of a larger degree of yield asymmetry improved the prediction of the fracture location; variations in the yield stress mainly affected the predicted failure force. We conclude that the implementation of asymmetric yielding in case-specific FE models improves the prediction of femoral bone strength.

Keywords:

• bone strength
• prediction
• finite element modelling
• yield asymmetry
• metastatic bone disease

Acknowledgements

This project has been funded by the Dutch Science Foundation NWO-STW (NPG.06778), the Furlong Research Charitable Foundation and Stichting Anna Fonds.

Notes

1. [email protected]

2. [email protected]

3. [email protected]

Additional information

Notes on contributors

Timo Meinders

1

Nico Verdonschot

2

Esther Tanck

3