Flow analysis of aortic dissection: comparison of inflow boundary conditions for computational models based on 4D PCMRI and Doppler ultrasound

Abstract

Computational hemodynamics quantifying the flow environment is an important tool in understanding aortic dissection. In this study, various inflow boundaries were applied on a patient-specific model and compared to the individualized velocimetry. The results indicated that the computations generally overestimated the flow volume and underestimated the wall shear stress. By quantifying the accuracy of the simulation results, two inflow settings were suggested. One was individualized, the PCMRI-extracted 4D flow information, and the other was averaged by healthy data, the ultrasound-extracted averaged flow waveform with parabolic velocity profile. This study might contribute to improving the precise computation of aortic dissection hemodynamics.

Keywords:

• Aortic dissection
• computational fluid dynamics
• boundary condition
• 4D PCMRI
• Doppler ultrasound

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This research was supported by the National Key R&D Program of China (2018AAA0102600), the National Natural Science Foundation of China (81970404, 81911530224 and 81770465) and the Beijing Municipal Science & Technology Commission (Z191100010618004), the Beijing Nova Program (Z181100006218008) and the Beijing Natural Science Foundation (Z190014 and L192010).