A new prenylated isoflavone from Derris scandens Benth

Abstract

The phytochemical study of the whole plant of Derris scandens (Leguminosae) has resulted in the isolation of a new isoflavone derivative, scandinone A (11), together with 11 known compounds (1–10, 12). Structural elucidations of these compounds were performed using spectroscopic methods especially 1D, 2D NMR, and mass spectral analyses. The α-glucosidase-inhibitory activity of the isolates was also evaluated.

Keywords:

• Derris scandens
• scandinone A
• isoflavones
• prenylated coumarins
• α-glucosidase enzyme inhibition

Acknowledgement

The authors thank Dr J. S. Yadav, Director, Indian Institute of Chemical Technology, for his constant encouragement.