Two new dammarane-type triterpene saponins from red American ginseng

Abstract

Two new dammarane-type triterpene saponins were isolated from the red American ginseng. The new saponins were named as pseudoginsenoside G₁ (1) and pseudoginsenoside G₂ (2). Their structures were elucidated by the combined analysis of NMR and mass spectrometry as 3-O-[β-d-glucopyranosyl-(1 → 2)-β-d-glucopyranosyl]-dammar-12-one-20S,24R-epoxy-3β,25-diol (pseudoginsenoside G₁) (1) and 3-O-[β-d-glucopyranosyl-(1 → 2)-β-d-glucopyranosyl]-dammar-12-one-20S,24S-epoxy-3β,25-diol (pseudoginsenoside G₂) (2).

Keywords:

• red American ginseng
• pseudoginsenoside G₁
• pseudoginsenoside G₂

Acknowledgements

We are grateful to the Jilin TongBao Chinese Traditional Medicine Science & Technology Development Co., Ltd. for providing the red American ginseng. We are also very grateful to Chun-Yu Wang (Key Laboratory for Supramolecular Structure and Materials of Ministry of Education, Jilin University) for the measurement of NMR spectra.