Two new limonoids from the stem barks of Chukrasia tabularis var. velutina

Abstract

Two new phragmalin-type limonoid orthoesters, C-15 enolic acyl type and 13/14/18-cyclopropanyl type, named chukvelutilide H (1) and tabularin R (2), together with three known limonoid orthoesters (3–5), were isolated from the stem barks of Chukrasia tabularis var. velutina. The structures of these two new compounds were elucidated on their extensive HR-ESI-MS, 1D, and 2D spectroscopic analysis including HSQC, HMBC, and ROESY experiments.

Keywords:

• Chukrasia tabularis var. velutina
• phragmalin-type limonoid
• orthoester

Acknowledgements

This research work was supported by the Key Project of National Natural Science Foundation of China (Grant No. 30830116) and the National Key Scientific and Technological Special Projects of China (2009ZX09502-011).