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Journal of Asian Natural Products Research Volume 13, 2011 - Issue 11
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Original Articles

Two new compounds from the endophytic fungus Colletotrichum sp. L10 of Cephalotaxus hainanensis

Gang Chen School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China
,
Hao-Fu Dai The Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Hainan, 571101, China
,
Yi Sha Department of Instrumental Analysis, Shenyang Pharmaceutical University, Shenyang, 110016, China
&
Yue-Hu Pei School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, ChinaCorrespondence[email protected]
Pages 1042-1046 | Received 18 May 2011, Accepted 16 Aug 2011, Published online: 10 Oct 2011
 
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Abstract

Two new compounds, 3-(4-methoxy-3-methyl-2-oxo-2H-pyran-6-yl)butyl pyroglutamate (1) and 2,2′-(1,1′-methylenebis(1H-indole-3,1-diyl))diethanol (2), were isolated from the endophytic fungus of Cephalotaxus hainanensis. Their structures were determined by means of chemical and spectroscopic analysis.

Acknowledgements

This research work was financially supported by the National Natural Science Foundation of China (No. 30860345), the National Nonprofit Institute Research Grant of CATAS-ITBB (No. ITBBZD0841), and the Ministry of Science and Technology ‘863’ project of China, Project No. 2007AA09Z413. Prof. Hao-Fu Dai offered the fermentation broth of the endophytic fungus L10.

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