Selaginellin M, a new selaginellin derivative from Selaginella pulvinata

Abstract

A new selaginellin derivative, selaginellin M (1), together with one known compound, selaginellin E (2), was isolated from Selaginella pulvinata. The structure of the new compound was elucidated and named as (R,S)-4-((4′-hydroxy-4-((2-hydroxyethoxy)methyl))-3-((4-hydroxyphenyl)ethynyl)biphenyl-2-yl)(4-hydroxyphenyl)methylene)cyclohexa-2,5-dienone on the basis of the spectroscopic data including UV, IR, 1D, and 2D NMR as well as HR-ESI-MS analysis.

Keywords:

• selaginella
• Selaginella pulvinata
• selaginellin M
• selaginellin E

Acknowledgements

This work was supported financially by grants from the National Natural Science Foundation of China (No. 30873149), Doctoral Program Foundation of Institutions of Higher Education of China (No. 20100162110057), Chinese Medicine Research Program of Hunan Province (Nos 2009059 and 2010004), National Innovation Experiment Program for University Students (No LA10031), Independent Exploration Program of Central South University (No 201011200235), and the Open-End Fund for the Valuable and Precision Instruments of Central South University.