Methoxylated fatty acids from the bark of Fraxinus sieboldiana

Abstract

Nine new fatty acid derivatives, including seven methoxylated (1, 2, and 4–8) and two hydroxylated (3 and 9) fatty acids, have been isolated from the ethanol extract of the stem bark of Fraxinus sieboldiana. Their structures were determined by spectroscopic methods including IR, MS, 1D, and 2D NMR experiments. The 3- or 9-methoxylated fatty acids are reported for the first time in nature.

Keywords:

• Fraxinus sieboldiana
• Oleaceae
• 3- or 9-methoxylated fatty acids
• 3- or 9-hydroxylated fatty acids

Acknowledgements

Financial support from the National Natural Sciences Foundation of China (NNSFC; Grant Nos 30825044 and 20932007) and the National Science and Technology Project of China (Nos 2009ZX09311-004 and 2009ZX09301-003-4-1) is acknowledged.