Two new C₁₉-diterpenoid alkaloids from Aconitum transsectum

Abstract

Two new C₁₉-diterpenoid alkaloids, named aconitramines D (1) and E (2), were isolated from the roots of Aconitum transsectum. Based on comprehensive spectroscopic analyses including IR, ESI-MS, HR-ESI-MS, and 1D and 2D NMR, their structures were elucidated as 18-demethoxyltransconitine A (1) and 8-O-anisoyl-14-hydroxylacoforesticine (2).

Keywords:

• Aconitum transsectum
• diterpenoid alkaloids
• aconitramines D and E

Acknowledgements

This work was financially supported by the 973 project of the Ministry of Sciences and Technology (No. 2009CB941300). The authors are grateful to the members of the staff of analytical group of State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, for the measurements of all spectra.