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Journal of Asian Natural Products Research Volume 14, 2012 - Issue 4
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Original Articles

Cichorins B and C: two new benzo-isochromenes from Cichorium intybus

Hidayat Hussain Department of Biological Sciences and Chemistry, College of Arts and Sciences, University of Nizwa, Birkat Al-Mouz, Nizwa, 616, Sultanate of OmanCorrespondence[email protected]
,
Javid Hussain Department of Biological Sciences and Chemistry, College of Arts and Sciences, University of Nizwa, Birkat Al-Mouz, Nizwa, 616, Sultanate of Oman; Department of Chemistry, Kohat University of Science and Technology, Kohat, Khyber Pakhtunkhwa, Pakistan
,
Samina Ali Department of Chemistry, Kohat University of Science and Technology, Kohat, Khyber Pakhtunkhwa, Pakistan
,
Ahmed Al-Harrasi Department of Biological Sciences and Chemistry, College of Arts and Sciences, University of Nizwa, Birkat Al-Mouz, Nizwa, 616, Sultanate of OmanCorrespondence[email protected]
,
Muhammad Saleem Department of Chemistry, The Islamia University of Bahawalpur, Baghdad Campus-ul-Jadid, Bahawalpur, 63000, Pakistan
,
Ghulam Abbas Miana Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan
,
Muhammad Riaz NUST Center of Virology and Immunology, National University of Science and Technology, H-12, Islamabad, Pakistan
,
Saeed Anwar Department of Chemistry, Islamia College Peshawar, University of Peshawar, Peshawar, Khyber Pakhtunkhwa, Pakistan
,
Sajjad Hussain Department of Chemistry, Post Graduate College Parachinar, Kurram Agency, Khyber Pakhtunkhwa, Pakistan
&
Liaqat Ali Department of Biological Sciences and Chemistry, College of Arts and Sciences, University of Nizwa, Birkat Al-Mouz, Nizwa, 616, Sultanate of Oman
 show all
Pages 297-300 | Received 30 Aug 2011, Accepted 21 Dec 2011, Published online: 01 Mar 2012
 
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Abstract

Two new benzo-isochromenes, named cichorins B (1) and C (2), were isolated from Cichorium intybus. The structures of the new compounds were elucidated by detailed spectroscopic analysis such as 1H, 13C NMR, COSY, HMQC, HMBC, and HR-EI-MS. Relative configurations of asymmetric centers of cichorins B and C were determined by the analysis of the 1H NMR coupling constants together with the 2D NOESY and 1D NOE experiments as well as from value.

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