Two new neolignans from the stems of Euonymus oblongifolius

Abstract

Two new neolignans, (+)-(7R,8R)-4-hydroxy-3,3′,5′-trimethoxy-8′,9′-dinor-8,4′- oxyneoligna-7,9-diol-7′-aldehyde (1) and ( − )-(7S,8R)-4-hydroxy-3,3′,5′-trimethoxy-8′, 9′-dinor-8,4′-oxyneoligna-7,9-diol-7′-aldehyde (2), were isolated from the stems of Euonymus oblongifolius. Their chemical structures were determined according to HR-ESI-MS, CD, 1D and 2D NMR spectroscopic analyses.

Keywords:

• Euonymus oblongifolius
• Neolignan
• Celastraceae

Acknowledgments

We deliver our sincere thanks to the Department of Instrumental Analysis, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College for the measurement of the IR, CD, NMR, MS, and HR-ESI-MS spectral data. This research program was supported by the National Natural Science Foundation of China (No. 21132009), National Science and Technology Project of China (2011ZX09307-002-01), and the program for Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China (IRT1007).