A new triterpenoid saponin from Gymnema sylvestre

Abstract

Besides four known compounds, a new triterpenoid saponin was isolated from the stems of Gymnema sylvestre. The structure of the new triterpenoid saponin was established as 3β,16β,22α-trihydroxy-olean-12-ene 3-O-β-d-xylopyranosyl-(1 → 6)-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside (1) on the basis of 1D and 2D NMR techniques, including COSY, HMBC, HMQC, and NOESY correlations. Four known compounds 2, 3, 4, and 5 were identified on the basis of spectroscopic data.

Keywords:

• Gymnema sylvestre
• triterpenoid saponin
• Asclepiadaceae

Acknowledgments

The authors are grateful to the International Science & Technology Cooperation Program of China (No. 2010DFB33260) and the Cooperation Program of Beijing Municipal Education Commission and the Program for New Century Excellent Talents in University (NCET-08-0746), and Program for the Development of Scientific and Technological Plan of Jilin (No. 20100122).