A new antibacterial phenanthrenequinone from Dendrobium sinense

Abstract

A new phenanthrenequinone, named denbinobin B (1), together with three known phenanthrenes was isolated from the whole plant of Dendrobium sinense T. Tang et F.T. Wang, an endemic and endangered orchid to Hainan Island. The new compound was elucidated using a combination of 1D, 2D NMR (COSY, HMQC, and HMBC) techniques, and HR-ESI-MS analyses. Compound 1 exhibited moderate antibacterial activity against Staphylococcus aureus with the diameter of the inhibition zone of 16.5 mm.

Keywords:

• Dendrobium sinense
• phenanthrenequinone
• denbinobin B
• antibacterial activity

Acknowledgments

This research was financially supported by International Cooperation Projects of Hainan Province (No. 2012GH001) and Fundamental Research Funds for Central Public Welfare Research Institutes (Chinese Academy of Tropical Agricultural Sciences, No. 1630052012014). It was also supported by National Natural Science Foundation of China (Nos 30860233 and 31160178) and partially supported by the State Key Subject of Botany at Hainan University (071001).

Notes

1. These authors contributed equally to this work.

Additional information

Notes on contributors

Xiu-Juan Chen

1

Wen-Li Mei

1