Coumarins from roots of Clausena excavata

Abstract

Two new coumarins, clauexcavatins A (1) and B (2), along with seven known ones (3–9), were isolated from the roots of Clausena excavata Burm. f. (Rutaceae). Their structures were elucidated on the basis of spectral data.

Keywords:

• Clausena excavata
• Rutaceae
• coumarin
• clauexcavatin A
• clauexcavatin B

Acknowledgements

This work was financially supported by the National Natural Science Foundation of China (U1032602, 91013002, and 30725048), the National New Drug Innovation Major Project of China (2011ZX09307-002-02), the National Basic Research Program of China (2009CB522300 and 2013CB127505), the Foundation of Chinese Academy of Sciences (Hundred Talents Program), and the Natural Science Foundation of Yunnan Province (2012GA003). The authors are grateful to the members of the analytical group from the State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, for measuring the [α], IR, UV, NMR, and mass spectra.