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Journal of Asian Natural Products Research Volume 15, 2013 - Issue 3
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Original Articles

Two new triterpenoids from the fungus Perenniporia maackiae

Hua Guo State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China; School of Chemistry and Life Science, Anshan Normal College, Anshan, 114005, China; Graduate University of Chinese Academy of Science, Beijing, 100049, China
,
Jing Si Institute of Microbiology, Beijing Forestry University, Beijing, 100083, China
,
Zheng-Hui Li State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China
,
Tao Feng State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China
,
Ze-Jun Dong State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China
,
Yu-Cheng Dai Institute of Microbiology, Beijing Forestry University, Beijing, 100083, China
&
Ji-Kai Liu State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, ChinaCorrespondence[email protected]
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Pages 253-257 | Received 07 Oct 2012, Accepted 23 Nov 2012, Published online: 18 Feb 2013
 
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Abstract

Two new triterpenoids, 3β-(2-methoxy-oxalyloxy)-24-methylene-lanost-8-en-21-oic acid (1) and 3β-(2-methoxy-oxalyloxy)-15α-hydroxy-24-methylene-lanost-8-en-21-oic acid (2), were isolated from cultures of the fungus Perenniporia maackiae, together with two previously known triterpenoids (3 and 4). Their structures were determined by spectroscopic methods, including 1D and 2D NMR, and MS analyses. All compounds were evaluated for their cytotoxic activities on five tumor cell lines.

Acknowledgements

This work was financially supported by National Basic Research Program of China (973 Program, 2009CB522300) and the National Natural Science Foundation of China (U1132607).

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