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Journal of Asian Natural Products Research Volume 15, 2013 - Issue 4
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New alkaloid from Streptomyces koyangensis residing in Odontotermes formosanus

Shu-Feng Bi Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, 210093, China; College of Life and Environment Sciences, Huangshan University, Huangshan, 245041, China
,
Zhi-Kai Guo Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, 210093, China
,
Nan Jiang School of Pharmacy, Nanjing Medical University, Nanjing, 210029, China
,
Rui-Hua Jiao Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, 210093, China
,
Hui-Ming Ge Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, 210093, China
&
Ren-Xiang Tan Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, 210093, ChinaCorrespondence[email protected]
Pages 422-425 | Received 11 Jun 2012, Accepted 13 Jan 2013, Published online: 18 Feb 2013
 
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Abstract

A new alkaloid was isolated from the ethyl acetate extract of the culture of a termite-associated Streptomyces koyangensis BY-4. The structure of 1 was elucidated by using MS, NMR, electronic circular dichroism data, and computational approaches. Compound 1 showed weak antimicrobial activities against a panel of test microbes.

Acknowledgments

This work was financially supported by NSFC (81172948 and 21132004), MOE (NCET-10-0477), MOST (2011AA09070204), and CPSF (2011M500898).

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