Uncinataflavone, a new flavonoid with a methyl benzoate substituent from Selaginella uncinata

Abstract

Uncinataflavone (1), a new flavonoid, together with four known compounds (2–5), was isolated from Selaginella uncinata (Desv.) Spring. Compounds 2 and 3 were isolated from the genus selaginella for the first time. The structure of the new compound was determined as methyl 3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl)-4-methoxybenzoate by means of spectroscopic evidence, including UV, IR, 1D and 2D NMR analyses as well as HR-ESI-MS. These compounds (1–5) were evaluated for the antioxidant activity in 1,1-diphenyl-2-picrylhydrazyl assay system.

Keywords:

• Selaginella uncinata
• flavonoid
• uncinataflavone
• antioxidant

Acknowledgements

This work was supported financially by grants from Outstanding doctor award grants of Central South University (No. 2011ybjz051), Doctoral Program Foundation of Institutions of Higher Education of China (No. 20100162110057), National Natural Science Foundation of China (No. 30873149), Chinese Medicine Research Program of Hunan Province (Nos 2009059 and 2010004), and Innovation Training Project of Hunan Province for University Students (No. BY12076).