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Journal of Asian Natural Products Research Volume 15, 2013 - Issue 4
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A new flavanol from Cynomorium songaricum

Shi-An Xie School of Pharmacy, Shihezi University, Shihezi, 832002, China
,
Guo-Yu Li School of Pharmacy, Shihezi University, Shihezi, 832002, China
,
Jian Huang School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China; Department of New Drug, Institute of Frontier Medical Sciences, Jilin University, Changchun, 130021, ChinaCorrespondence[email protected]
,
Ya-Xin Zheng School of Pharmacy, Shihezi University, Shihezi, 832002, China
,
Hang-Yu Wang School of Pharmacy, Shihezi University, Shihezi, 832002, China
,
Ke Zhang School of Pharmacy, Shihezi University, Shihezi, 832002, China; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China
,
Hong-Ying Gao School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China
,
Yong Tan School of Pharmacy, Shihezi University, Shihezi, 832002, China
,
Wen Chen School of Pharmacy, Shihezi University, Shihezi, 832002, China
,
Hong Chen School of Pharmacy, Shihezi University, Shihezi, 832002, China
,
Ping-Ya Li Department of New Drug, Institute of Frontier Medical Sciences, Jilin University, Changchun, 130021, China
&
Jin-Hui Wang School of Pharmacy, Shihezi University, Shihezi, 832002, China; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, ChinaCorrespondence[email protected]
 show all
Pages 413-416 | Received 29 Jul 2012, Accepted 01 Nov 2012, Published online: 06 Mar 2013
 
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Abstract

A new flavanol, named songarin A (1), was isolated from Cynomorium songaricum Rupr. The structure was established on the basis of spectroscopic methods including 2D NMR techniques. Compound 1 displayed the protective effect against d-galactosamine-induced HepG2 damage and reduced the damage from 58.64% to 22.26%.

Acknowledgments

This work was financially supported by National Key Technology R&D Program (2012BAI30B02), National Natural Science Foundation (U1170302), and Shenyang Science & Technology Program (F12-157-9-00).

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