Two novel dammarane-type compounds from the leaves and stems of Panax quinquefolium L.

Abstract

Two new dammarane-type compounds were isolated from the leaves and stems of Panax quinquefolium L. The new compounds were named as pseudo-ginsenoside RT₆ (1) and pseudoginsengenin R₁ (2). The structures of the new compounds were elucidated by the combined analysis of NMR and HR-ESI-MS as (20S,24R)-6-O-β-d-glucopyranosyl-dammar-3-one-20,24-epoxy-6α,12β,25-triol (1) and (20S,24R)-dammar-3-one-20,24-epoxy-6α,12β,25-triol (2).

Keywords::

• Panax quinquefolium
• pseudoginsenoside RT₆
• pseudoginsengenin R₁

Acknowledgements

We are very grateful to Dr Chun-Yu Wang (Key Laboratory for Supramolecular Structure and Materials of Ministry of Education, Jilin University) for the measurement of NMR spectra.