Two new alkaloids from Corydalis humosa

Abstract

Two new alkaloids, named 1,1-dimethyl-6-methoxy-7-hydroxyl-1,2,3,4-tetrahydroisoquinoline (1) and (1R)-(4-hydroxybenzyl)-7-hydroxyl-8-O-β-d-glucopyranosyl-1,2,3,4-tetrahydroisoquinoline (2), together with 11 known compounds (3–13), were isolated from the tubers of Corydalis humosa. Their structures were elucidated on the basis of their spectroscopic and chemical evidence.

Keywords::

• Papaveraceae
• Corydalis humosa
• alkaloids
• structure elucidation

Acknowledgments

The authors are grateful to Prof. Sui-Qing Chen (Henan University of Traditional Chinese Medicine, China) for collecting and identifying the plant material, and thank Dr Yan-Li Zhang (Henan University of Traditional Chinese Medicine, China) for recording the NMR spectra.