New oleanane-type triterpenoid saponins isolated from the seeds of Celosia argentea

Abstract

Three new oleanane-type triterpenoid saponins named celosins H (1), I (2), and J (3) were isolated from the seeds of Celosia argentea L. Their structures were characterized as 3-O-β-d-xylopyranosyl-(1 → 3)-β-d-glucuronopyranosyl-polygalagenin 28-O-β-d-glucopyranosyl ester, 3-O-β-d-glucuronopyranosyl-medicagenic acid 28-O-β-d-xylcopyranosyl-(1 → 4)-α-l-rhamnopyranosyl-(1 → 2)-β-d-fucopyranosyl ester, and 3-O-β-d-glucuronopyranosyl-medicagenic acid 28-O-α-l-arabinopyranosyl-(1 → 3)-[β-d-xylcopyranosyl-(1 → 4)]-α-l-rhamnopyranosyl-(1 → 2)-β-d-fucopyranosyl ester by NMR, MS, and chemical evidences, respectively. In our opinion, celosins H–J could be used as chemical markers for the quality control of C. argentea seeds.

Keywords::

• Celosia argentea
• triterpenoid saponins
• celosins H–J
• NMR

Acknowledgments

This work was financially supported by the special program of Hong Kong Chinese Materia Medica Standards (SHK 2012-22) from Department of Health, the Government of the Hong Kong Special Administrative Region of the People's Republic of China. The authors thank the technical support from National Institute for Food and Drug Control.

Notes

^1. These authors contributed equally to this work.