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Journal of Asian Natural Products Research Volume 16, 2014 - Issue 5
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Articles

Three new vibralactone-related compounds from cultures of Basidiomycete Boreostereum vibrans

Gang-Qiang WangCollege of Chemistry and Chemical Engineering, Hunan University, Changsha410082, China;State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, China
,
Kun WeiState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, ChinaCorrespondence[email protected] [email protected]
,
Ling ZhangState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, China
,
Zheng-Hui LiState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, China
,
Qiu-An WangCollege of Chemistry and Chemical Engineering, Hunan University, Changsha410082, China
&
Ji-Kai LiuState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, ChinaCorrespondence[email protected] [email protected]
Pages 447-452 | Received 08 Oct 2013, Accepted 03 Mar 2014, Published online: 01 Apr 2014
 
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Abstract

Three new compounds, named as vibralactones K–M (1–3), together with vibralactone (4) have been isolated from cultures of the Basidiomycete Boreostereum vibrans. Their structures were determined on the basis of spectroscopic evidences (1D and 2D NMR, HRMS, UV, and IR data), chemical methods and literature data. None of the compounds was cytotoxic against five human cancer cell lines and showed inhibitory activity on the pancreatic lipase.

Acknowledgments

This project was financially supported by National Natural Science Foundation of China (Nos 81102348 and 21302194) and Hunan Province Innovation Foundation for Postgraduate (CX2012B160).

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