Two new flavonols from Cudrania cochinchinensis

Abstract

Two new flavonols, 6-p-hydroxybenzyl kaempferol (1) and 6-p-hydroxybenzyl quercetin (2), together with six known compounds were isolated from the roots of Cudrania cochinchinensis and their structures elucidated on the basis of spectroscopic methods. Their antioxidant capacities were evaluated by 1,1-diphenyl-2-picryl-hydrazyl and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical-scavenging assays. The results suggested that compounds 2, 4, and 7 showed significant radical-scavenging activities.

Keywords::

• Cudrania cochinchinensis
• flavonols
• 6-p-hydroxybenzylkaempferol
• 6-p-hydroxybenzyl quercetin
• antioxidant activity

Acknowledgments

The authors thank Mrs Yan Xue and Mrs Mei-feng Xu of the National Center of Biomedical Analysis for the measurements of the MS and NMR spectra.

Notes

^1. These authors contributed equally to this work.