Phenolic glycosides from Glycosmis pentaphylla

Abstract

Three new phenolic glycosides, named as glycopentosides A–C (1–3), along with nine known compounds were isolated from the n-BuOH extract of stems of Glycosmis pentaphylla. Their structures were determined by using spectroscopic and chemical methods. Bioassay showed that compound 10 (tachioside) could inhibit nitric oxide production in lipopolysaccharides-stimulated RAW 264.7 cells with IC₅₀ value of 12.14 μM.

Keywords::

• Rutaceae
• Glycosmis pentaphylla
• phenolic glycosides
• nitric oxide production

Acknowledgments

This work was financially supported by the Natural Science Foundation of Hubei Province, China (2013CFB450 and 2013CFA013) and Grant of National Key Technology R&D Program in the 12th Five Year Plan of China (2012BAI27B06).