Three new polyunsaturated lipids from a Guangxi marine sponge Haliclona sp.

Abstract

Three new polyunsaturated lipids, (6Z,9Z,12Z,15Z)-octadeca-6,9,12,15-tetraen-3-one (1), (6Z,9Z,12Z,15Z)-1-bromooctadeca-6,9,12,15-tetraen-3-one (2), and (Z)-ethyl docos-5-enoate (3), together with two known polyunsaturated lipids, 4(Z),7(Z),10(Z)-tridecatrienoic acid (4) and (6Z,9Z,12Z,15Z)-octadeca-1,6,9,12,15-pentaen-3-one (5), were isolated from the marine sponge Haliclona sp., which was collected from Guangxi, using HSCCC and HPLC methods. Chemical structures of the five compounds were elucidated by spectroscopic techniques.

Keywords::

• marine sponge
• Haliclona sp
• polyunsaturated lipids
• structural elucidation

Acknowledgments

This work was financially supported by grants from the National Natural Science Foundation of China (NSFC) (81102371), Natural Science Foundation of Tianjin, China (10JCYBJC15000), and Tianjin Higher Education Science and Technology Development Project (20130105).

Disclosure statement

No potential conflict of interest was reported by the authors.

Notes

^1. These authors contributed equally to this study.