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Journal of Asian Natural Products Research Volume 17, 2015 - Issue 11
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Articles

Two new illudin type sesquiterpenoids from cultures of Phellinus tuberculosus and Laetiporus sulphureus

Jiang-Bo HeSchool of Medicine, Kunming University, Kunming650214, China;State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, ChinaView further author information
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Jian TaoSchool of Medicine, Kunming University, Kunming650214, ChinaView further author information
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Xi-Song MiaoSchool of Medicine, Kunming University, Kunming650214, ChinaView further author information
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Yun-Ping FengSchool of Medicine, Kunming University, Kunming650214, ChinaView further author information
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Wei BuDepartment of Pharmacy, Xijing Hospital, Fourth Military Medical University, Xi'an710032, ChinaView further author information
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Ze-Jun DongState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, ChinaView further author information
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Zheng-Hui LiState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, ChinaView further author information
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Tao FengState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, ChinaCorrespondence[email protected] [email protected]
View further author information
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Ji-Kai LiuState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, ChinaView further author information
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Pages 1054-1058 | Received 23 Dec 2014, Accepted 10 Apr 2015, Published online: 22 May 2015
 
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Abstract

Chemical investigation on the cultures of Phellinus tuberculosus and Laetiporus sulphureus lead to the isolation of two new illudin-type sesquiterpenoids (phellinuin J and sulphureuine A). Their structures were elucidated by 1D, 2D NMR and MS spectroscopic data. These compounds were purposely evaluated for their cytotoxicity against HL-60, SMMC-7721, A549, MCF-7, and SW480 cell lines.

Additional information

Funding

This project was financially supported by the National Natural Sciences Foundation of China [grant number U1132607], [grant number 81102346]; Natural Sciences Foundation of Yunnan Province [grant number 2011FB099]; West Light Foundation of The Chinese Academy of Sciences [grant number 2013312D11016].

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