Two new triterpenoid saponins from the aerial parts of Anemone taipaiensis

Abstract

Phytochemical study on the aerial parts of Anemone taipaiensis for the first time led to the isolation of two new oleanane-type triterpenoid saponins 1 and 2, together with four known saponins (3–6). Their structures were elucidated by extensive spectroscopic analysis and chemical evidences. Saponins 2–4 exhibited cytotoxicity against human glioblastoma U251MG cell line with IC₅₀ values ranging from 1.56 to 80.62 μM.

Keywords::

• Anemone taipaiensis
• Ranunculaceae
• aerial part
• triterpenoid saponin
• cytotoxicity

Disclosure statement

No potential conflict of interest was reported by the authors.

Notes

^1. Hui Li and Xiao-Yang Wang contributed equally to this work.

Additional information

Funding

This work was financially supported by the National Natural Science Foundation of China [No. 81274029], the Science and Technology Innovation Project of Shaanxi Province, China [No. 2013KTCL03-10], and the Administration of Traditional Chinese Medicine of Shaanxi Province, China [No. zy36].