Abstract
Biotransformations of icariin (1) by cell suspension cultures of Glycyrrhiza uralensis and Morus alba yielded two new metabolites, icaruralins A and B (2 and 3), and one known metabolite, baohuoside I (4). Their structures were determined on the basis of extensive spectroscopic analysis. This is the first report that the cell suspension cultures of G. uralensis and M. alba possess deglycosylation functionality.
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No potential conflict of interest was reported by the author(s).
Supporting information available
The HPLC-UV analysis of biotranformation of 1, HR-ESI-MS, IR, CD, 1D, and 2D NMR spectra of 2–3, the 1H NMR and 13C NMR spectra for 4. This material is available free of charge via the Internet at http://www.tandfonline.com/toc/ganp20/current
Notes
1. These authors contributed equally to this work.