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Articles

Two new lignans from twigs of Aglaia odorata

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Pages 147-152 | Received 02 Mar 2015, Accepted 28 May 2015, Published online: 24 Jul 2015
 

Abstract

HPLC-guided separation of twigs of Aglaia odorata led to the isolation of eight lignans, including two new ones, 3′-methoxy-N-demethylrocaglamide (1) and 4′-O-demethyl-deacetylaglaxiflorin A (2). Compound 1 showed excellent cytotoxicity against three human cancer cell lines, HeLa, SGC-7901 gastric cancer, and A-549 lung cancer with the values of 0.32, 0.12, and 0.25 μM, respectively.

Abstract

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This work was financially supported by the National Natural Science Foundation of China [grant number 21172225], [grant number 31370377); the Young Academic and Technical Leader Raising Foundation of Yunnan Province [grant number 2010CI049]; and XiBuZhiGuang Project of the Chinese Academy of Sciences.

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