Two new 13,14:14,15-disecopregnane-type compounds from the roots of Cynanchum paniculatum

Abstract

Two new 13,14:14,15-disecopregnane-type compounds glaucogenin F (1), glaucogenin F 3-O-β-D-oleandropyranoside (2), together with three known compounds cynapanoside A (3), cynatratoside A (4), and neocynapanogenin F 3-O-β-D-oleandropyranoside (5) were isolated from the 95% ethanol extract of the roots of Cynanchum paniculatum. The structures of new compounds were elucidated on the basis of extensive spectroscopic analyses, including 1D and 2D NMR, HRESIMS and NOESY.

Keywords::

• Asclepiadaceae
• Cynanchum paniculatum
• 13,14:14,15-disecopregnane
• glaucogenin F

Acknowledgment

This paper was financially supported by Program for Innovative Research Team of the Ministry of Education and Program for Liaoning Innovative Research Team in University.

Disclosure statement

No potential conflict of interest was reported by the authors.