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Journal of Asian Natural Products Research Volume 18, 2016 - Issue 8
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Articles

Three new oxazoline alkaloids from Gymnotheca chinensis

Shi-Ji XiaoSchool of Pharmacy, Zunyi Medical Universty, Zunyi563000, ChinaCorrespondence[email protected]
,
Da-Le GuoChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu610041, China
,
Mao-Sheng ZhangSchool of Pharmacy, Zunyi Medical Universty, Zunyi563000, China
,
Fang ChenCollege of Life Science, Sichuan University, Chengdu610041, China
,
Li-Sheng DingChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu610041, China
&
Yan ZhouChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu610041, ChinaCorrespondence[email protected]
Pages 719-723 | Received 29 Nov 2015, Accepted 21 Jan 2016, Published online: 07 Mar 2016
 
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Abstract

Three novel oxazoline alkaloids, 1-oxa-3-azaspiro [4.5] dec-2-ene-8-one (1), 1-oxa-3-azaspiro [4.5] dec-2, 6-diene-8-one (2), and 1-oxa-3-azaspiro [4.5] dec-10-methoxy-2, 6-diene-8-one (3) were isolated from the methanol extract of the whole plant of Gymnotheca chinensis. The chemical structures were established by means of spectroscopic analysis including one- and two-dimensional NMR spectroscopy.

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