Two new 4,6-dimethyl-3,4-dihydrochromen-2-one derivatives from Craterellus odoratus

Abstract

Two rare types of 4,6-dimethyl-3,4-dihydrochromen-2-one derivatives, named cralactones A and B (1 and 2), were isolated from the culture broth of Craterellus odoratus. The structures of the new ones were established on the basis of extensive spectroscopic analysis, and it was found that the new compounds did not show pancreatic lipase inhibitory activity. Compounds 1 and 2 are the first examples of 4,6-dimethyl-3,4-dihydrochromen-2-one.

Keywords:

• Craterellus odoratus
• 4,6-dimethyl-3,4-dihydrochromen-2-one
• cralactone
• pancreatic lipase