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Journal of Asian Natural Products Research Volume 19, 2017 - Issue 7
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Original Articles

Sesquiterpenoids from the twigs and leaves of Fokienia hodginsii

Xing-De WuState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, China
,
Wen-Wen ZhongState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, China;Biomedical Engineering Research Center, Kunming Medical University, Kunming650500, China
,
Lin-Fen DingSchool of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming650500, China
,
Wen-Chao TuSchool of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming650500, China
,
Hui YangSchool of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming650500, China
,
Xun GongState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, China
,
Li-Yan PengState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, China
,
Yan LiState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, China
,
Zhong-Zhi XuInstitute of Alpine Economic Plant, Yunnan Academy of Agricutural Science, Lijiang674100, ChinaCorrespondence[email protected]
&
Qin-Shi ZhaoState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming650201, ChinaCorrespondence[email protected]
 show all
Pages 666-672 | Received 11 Apr 2016, Accepted 08 Oct 2016, Published online: 17 Dec 2016
 
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Abstract

A rare carotane-type sesquiterpenoid, forkienin A (1), a new eudesmane-type sesquiterpenoid, forkienin B (2), and a new natural eudesmane-type sesquiterpenoid, forkienin C (3), were isolated from the twigs and leaves of Fokienia hodginsii, along with eight known sesquiterpenoids. The structures of the new compounds were elucidated on the basis of their spectroscopic analysis, including 1D and 2D NMR methods. All compounds were evaluated for cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines.

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