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Journal of Asian Natural Products Research Volume 19, 2017 - Issue 9
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Articles

The first total synthesis of anemarchalconyn and anemarcoumarin A

Jing-Xia ZhangAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu611137, China
,
Zhe-Yu LiAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu611137, China
,
Yu-Chi WangAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China
,
Wen-Bo MaAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China
,
Ming HouAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China
,
Sheng-Hua CaoAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China
,
Ke-Hui TangAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China
&
Hong-Bo DongAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, ChinaCorrespondence[email protected]
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Pages 903-909 | Received 13 Sep 2016, Accepted 19 Dec 2016, Published online: 22 Feb 2017
 
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Abstract

Anemarchalconyn (1) and anemarcoumarin A (2), the natural bioactive compounds isolated from the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae), were first totally synthesized using easily available materials in short, convenient routes with overall yields of 32 and 48%.

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