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Journal of Asian Natural Products Research Volume 19, 2017 - Issue 11
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Articles

Two new compounds from the green peel of Juglans mandshurica

Jing LiXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China
,
Kang-Ping XuXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China
,
Zhen-Xing ZouXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China
,
Hui ZouXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China
,
Hong-Ping LongThe First Hospital of Hunan University of Chinese Medicine, Changsha410007, China
,
Lei-Hong TanXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, ChinaCorrespondence[email protected]
,
Rui-Huan LiuXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China
,
Yi-Kun WangXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China
,
Ping-Sheng XuXiangya Hospital of Central South University, Changsha410008, China
&
Gui-Shan TanXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China;Xiangya Hospital of Central South University, Changsha410008, ChinaCorrespondence[email protected]
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Pages 1087-1092 | Received 19 Sep 2016, Accepted 11 Feb 2017, Published online: 17 Mar 2017
 
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Abstract

A new cyclic diarylheptanoid (1) and a new flavone glucoside (2), along with seven known compounds, were isolated from the green peel of Juglans mandshurica. Their structures were elucidated based on extensive spectroscopic analyses. Moreover, the cytotoxicity against NCI-H460, A549, and K562 cancer cells of compounds 1–6 was evaluated. The results showed that compound 3 exhibited moderate inhibitory potency against the growth of three cell lines.

Acknowledgments

The authors gratefully acknowledge the NMR measurements from the Modern Analysis and Testing Centre of CSU.

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