Two new isobenzofuranone derivatives from the fruiting bodies of Hericium erinaceus

Abstract

Two new isobenzofuranone derivatives erinaceolactones G and H (1 and 2) were isolated from the ethanolic extract of fruiting bodies of Hericium erinaceus. Their structures were characterized on the basis of spectroscopic evidences. Compound 2 was suggested to be racemic by specific rotation, which was resolved by chiral HPLC into enantiomers.

Keywords:

• Hericium erinaceus
• isobenzofuranone
• erinaceolactone G
• erinaceolactone H

Acknowledgments

The authors gratefully acknowledge the NMR measurements from the Modern Analysis and Testing Centre of Central South University.