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Isoprenylated phenolic compounds with tyrosinase inhibition from Morus nigra

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Pages 488-493 | Received 14 Dec 2016, Accepted 29 Jun 2017, Published online: 30 Nov 2017
 

Abstract

A new isoprenylated sanggenon-type flavanone, nigrasin K (1), together with three known analogs (24) and five known Diels–Alder adducts (59), were isolated from the twigs of Morus nigra. Their structures were elucidated by spectroscopic methods. Sanggenon M (2), chalcomoracin (5), sorocein H (6), kuwanon J (7), sanggenon C (8), and sanggenon O (9) showed significant inhibitory effects on mushroom tyrosinase.

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