Antiviral phenolics from Antenoron filiforme var. neofiliforme

Abstract

Two new phenolics, 1,3-di-O-p-coumaroyl-2′,6′-di-O-acetylsucrose (1) and quercetin 3-O-β-D-apiofuranoyl-(1→2)-α-L-rhamnopyranoside (2), along with nine known compounds (3–11), were isolated from the whole plants of Antenoron filiforme var. neofiliforme. Their chemical structures were characterized on the basis of various spectroscopic techniques. This is the first report of the isolation of phenylpropanoid sucrose (1, 3–4) from the genus Antenoron. The bioassay results showed that compound 11 exhibited antiviral activity against the Coxsackie virus B3 (CVB3).

Keywords:

• Polygonaceae
• Antenoron filiforme var. neofiliforme
• phenolics
• phenylpropanoid sucrose
• antiviral activity
• CVB3

Acknowledgments

The authors are grateful to Research Professor Ce-Ming Tan, Jiujiang Forest Herbarium, for authentication of the plant material. Thanks are also given to Research Professor Tao Peng, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, for the anti-CVB3 activity assay.