Advanced search
Publication Cover
Journal of Asian Natural Products Research Volume 20, 2018 - Issue 10
Submit an article Journal homepage
113
Views
4
CrossRef citations to date
0
Altmetric
Articles

Two new ent-kaurane diterpenes from the stems of Eurya chinensis

Jia-Ling SongProgram for Natural Product Chemical Biology, Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou510650, China;College of Life Sciences, University of Chinese Academy of Sciences, Beijing100049, China
,
Yao YuanProgram for Natural Product Chemical Biology, Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou510650, China;College of Life Sciences, University of Chinese Academy of Sciences, Beijing100049, China
,
Ling-Hui NieCollege of Traditional Chinese Medicine, Southern Medical University, Guangzhou510515, China
,
Bai-Lin LiProgram for Natural Product Chemical Biology, Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou510650, China;College of Life Sciences, University of Chinese Academy of Sciences, Beijing100049, China
,
Xu-Bing QinProgram for Natural Product Chemical Biology, Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou510650, China;College of Life Sciences, University of Chinese Academy of Sciences, Beijing100049, China
,
Yan LiProgram for Natural Product Chemical Biology, Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou510650, China;College of Life Sciences, University of Chinese Academy of Sciences, Beijing100049, China
,
Jie-Wei WuProgram for Natural Product Chemical Biology, Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou510650, ChinaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-0555-6086
ORCID Icon &
Sheng-Xiang QiuProgram for Natural Product Chemical Biology, Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou510650, ChinaCorrespondence[email protected]
 show all
Pages 962-968 | Received 22 Mar 2017, Accepted 25 Aug 2017, Published online: 11 Sep 2017
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

Two new ent-kaurane diterpenes (1–2), together with five known analogs, were isolated from the stems of Eurya chinensis. The structures of new compounds were established by extensive analysis of mass spectrometric and 1D and 2D NMR spectroscopic data. Compound 3 exhibited noticeable anti-inflammatory activity as denoted by inhibiting LPS-induced nitric oxide (NO) production in RAW264.7 cells with an IC50 value of 7.82 μM. Compound 4 showed potent cytotoxic activity against human cancer cell lines NCI-H46, HepG2 and SW480 with IC50 values ranging from 7.45 to 8.54 μM.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 426.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.