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Journal of Asian Natural Products Research Volume 20, 2018 - Issue 12
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Articles

First total synthesis of a new phenylpropanoid glycoside: natural cytotoxic compound from Cirsium japonicum

Hong-Bo DongAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, ChinaCorrespondence[email protected]
[email protected]
,
Ming HouAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China
,
Wen-Bo MaAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China
,
Jing-Xia ZhangAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu611137, China
,
Zhe-Yu LiAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu611137, China
,
Hong-Bing LuoAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China
,
Ke-Hui TangAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China
&
Sheng-Hua CaoAntibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu610052, China
 show all
Pages 1154-1161 | Received 31 May 2017, Accepted 11 Sep 2017, Published online: 26 Sep 2017
 
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Abstract

Phenylpropanoid glycoside compound 1, the natural anti-tumor compound isolated from the erial parts of Cirsium japonicum, was first totally synthesized using easily available materials in short, convenient route with overall yield of 13.9%.

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