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Journal of Asian Natural Products Research Volume 20, 2018 - Issue 11
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Articles

Phenolic glycosides from Lavandual angustifolia

Nigary YadikarThe Key Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi830011, China;State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, University of Chinese Academy of Sciences, Beijing100039, China
,
Khayrulla BobakulovInstitute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent100170, Uzbekistan
&
H. A. AisaThe Key Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi830011, China;State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi830011, ChinaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-4652-6879
ORCID Icon
Pages 1028-1037 | Received 08 Jul 2017, Accepted 06 Dec 2017, Published online: 27 Dec 2017
 
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Abstract

Four new phenolic glycosides (1–4), together with 12 known ones (5–16), were isolated from the essential oil extraction waste of Lavandula angustifolia. Their structures were unequivocally determined by extensive spectroscopic analysis (1D and 2D NMR, HR-ESI-MS, UV, and optical rotation), chemical method, and comparison with data reported in the literature. The antioxidant activities of all compounds and new compounds’ influence on melanin content in B16 melanoma cells were examined, which indicated that compounds 1, 8, 13 had a certain degree of DPPH free radical scavenging activities, while only compound 2 could increase the melanin content with a dose-dependent manner.

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