Two new chromene derivatives from Artemisia songarica

Abstract

Two new chromene derivatives, songaricachromenes A (1) and B (2), were isolated from Artemisia songarica, along with 10 known compounds (3–12). The structures and stereochemistry of the new compounds were elucidated by analyses of the NMR, MS, and electronic circular dichroism (ECD) data. All the isolates (1–12) were evaluated for their NO inhibitory effects on LPS-stimulated BV-2 microglial cells.

Keywords:

• Compositae; Artemisia songarica
• chromene
• NO inhibition

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was financially supported by National Natural Science Foundation of China (NSFC, No. 81373294) and National Key Technology R&D Program “New Drug Innovation” of China (No. 2018ZX09711001-008-003).