Abstract
A new sesquiterpenoid ester glycoside (1) and a new monoterpenoid ester glycoside (2) have been isolated from an ethanol extract of the twigs of Litsea cubeba. Their structures were elucidated by extensive 1D- and 2D-NMR experiments, and the absolute configurations were determined by chemical methods, specific rotation, and a combination of experimental and theoretically calculated electronic circular dichroism spectra. Compound 1 exhibited selective cytotoxicity against A549 and HCT-8 cell lines with the IC50 values of 8.9 and 9.6 μM, respectively.
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Disclosure statement
No potential conflict of interest was reported by the authors.
Supplementary material
Supplementary data associated with this article, including, 1H NMR spectrum of compound 1a, 1D, and 2D NMR spectra of compounds 1 and 2 can be found in the online version.