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Journal of Asian Natural Products Research Volume 22, 2020 - Issue 7
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Original Articles

Two new sesquiterpenoids from agarwood originated from Aquilaria sp.

Hao TianKey Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; ;Institute of Tropical Agriculture and Forestry, Hainan University, Haikou 570228, China; View further author information
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Hao WangKey Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; ;Hainan Engineering Research Center of Agarwood, Haikou 570228, ChinaView further author information
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Li YangKey Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; ;Hainan Engineering Research Center of Agarwood, Haikou 570228, ChinaView further author information
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Cui-Juan GaiKey Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; ;Hainan Engineering Research Center of Agarwood, Haikou 570228, ChinaView further author information
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Wen-Hua DongKey Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; ;Institute of Tropical Agriculture and Forestry, Hainan University, Haikou 570228, China; View further author information
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Wei LiKey Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; ;Hainan Engineering Research Center of Agarwood, Haikou 570228, ChinaView further author information
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Wen-Li MeiKey Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; ;Hainan Engineering Research Center of Agarwood, Haikou 570228, ChinaCorrespondence[email protected]
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Hao-Fu DaiKey Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; ;Hainan Engineering Research Center of Agarwood, Haikou 570228, ChinaCorrespondence[email protected]
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Pages 626-631 | Received 24 Dec 2018, Accepted 15 Apr 2019, Published online: 02 May 2019
 
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Abstract

Two new sesquiterpenoids (1 and 2), together with two known sesquiterpenoids (3 and 4), were isolated from agarwood originated from Aquilaria sp. Their structures were elucidated by extensive spectroscopic methods including 1D and 2D NMR, IR, HRESIMS, and comparison with the literatures. All compounds were evaluated for cytotoxicity against five human cancer cell lines, but none of them displayed significant activity.

Disclosure statement

No potential conflict interest was reported by the authors.

Additional information

Funding

This research was financially supported by Innovative Research Team Grant of the Natural Science Foundation of Hainan Province [grant No. 2017CXTD020], China Agriculture Research System (CARS-21), and Central Public-Interest Scientific Institution Basal Research Fund for Innovative Research Team Program of CATAS (17CXTD-15).

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