Two new ent-atisane diterpenes from Sapium sebiferum

Abstract

Two new ent-atisane diterpenes, sebiferumnins K and L (1 and 2), were isolated from the branches of Sapium sebiferum, together with four known compounds, ent-3-oxoatis-16α, 17-acetonide (3), ent-l6α, 17-dihydroxyatisan-3-one (4), ent-atisane-3β, 16α, 17-triol (5), ent-3α-hydroxyatis-16α,17-acetonide (6). The structures of these two ent-atisane diterpenes were elucidated by extensive analyses of the spectroscopic data.

Keywords:

• Euphorbiaceae
• Sapium sebiferum
• atisane diterpene
• sebiferumnin K
• sebiferumnin L

Acknowledgements

This study was financially supported by Yunnan Applied Basic Research Projects under contract number 2018FD164, and we acknowledge the Analysis Center of the Kunming Institute of Botany measuring the MS, UV, CD and NMR spectra.

Disclosure statement

No potential conflict of interest was reported by the authors.