Anti-inflammatory active components of the roots of Datura metel

Abstract

One new phenolic glycoside, methyl 3,4-dihydroxyphenylacetate-4-O-[2-O-β-D-apisoyl-6-O-(2-hydroxybenzoyl)]-β-D-glucopyranoside (1), together with 10 known compounds (2–11), were isolated from the roots of Datura metel. The structures of these compounds were elucidated on the basis of their spectroscopic data. Furthermore, the in vitro anti-inflammatory activities of compounds 1–11 were evaluated.

Graphical Abstract

Keywords:

• Solanaceae
• Datura metel
• phenolic glycoside
• anti-inflammatory activity

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This work was financially supported by the Guidance Plan of Science and Technology Research and Development of Shijiazhuang (No. 171461533).