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Abstract
This work obtained and identified pterocephanoside A (1), one new iridoid glucoside derivative with rare structure of three iridoid glycosides linked to cyclopenta[c]pyran-3(1H)-one, and 10 known iridoids (2–11) from Pterocephalus hookeri through silica gel column chromatography and semi-preparative HPLC. The structure of the new compound was confirmed by 1D and 2D NMR and HRMS data analysis. Compounds 1 and 2 were isolated from this plant for the first time. The iridoids mostly possessed seco-iridoid subtype and iridoid subtype skeletons from P. hookeri. Compounds 1, 3, 4, and 6–11 showed weak anti-inflammatory activity.
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Disclosure statement
No potential conflict of interest was reported by the authors.
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Funding
This work was supported by the National Natural Science Foundation of China [grant number 81903922]; National Key Research and Development Program of China [grant number 2017YFC1703900]; Xinglin Scholars Research Promotion Project of Chengdu University of Traditional Chinese Medicine (BSH2019002).