Two new quinic acid derivatives from the leaves of Schisandra chinensis

Abstract

Two new (1-2) and three known quinic acid derivatives (3-5) were isolated from the leaves of Schisandra chinensis (Turcz) Baill. The structures of the compounds were determined by spectroscopic methods, especially the NMR techniques, and also by comparison with reported data in the literature. The cytotoxicity activities of these compounds were evaluated on human tumor cell lines LN229 and three of them showed a certain activity.

Keywords:

• Magnoliaceae
• quinic acid derivatives
• Schisandra chinensis
• leaves
• spectroscopic methods
• tumor cell lines

Disclosure statement

No declaration of competing interest was reputed by the authors.

Additional information

Funding

This work was financially supported by the National Key Research and Development Project (2018YFC1707100), Heilongjiang University of Chinese medicine Founds (2018pt01, 2018bs03).