Two new flavonol glycosides from Selaginella tamariscina

Abstract

Two new flavonol glycosides 3,5,7-trimethoxyflavone-4'-O-[5'''-O-p-coumaroyl-β-D-apiofuranoyl-(1'''→2'')-β-D-glucopyranoside] (1) and 3,5,7-trimethoxyflavone −4'-O-β-D-glucopyranoside (2) were isolated from Selaginella tamariscina. The structures of 1 and 2 were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses and HRESIMS spectrometry. Two compounds were evaluated for cytotoxic activities against A-375, MCF-7, MDA-MB-231 and MDA-MB-468 cell lines by MTT assay. Unfortunately, two compounds displayed no cytotoxic activities.

Graphical Abstract

Keywords:

• Selaginellaceae
• Selaginella tamariscina
• flavonol glycoside
• chemical constituents
• cytotoxicity

Additional information

Funding

This work was financially supported by the University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province (No. 2020CX30).